Home | Research | Lab Personnel | Publications | Links

 

Neural Network Patterning

Journal Articles and Book Chapters

D.W. Branch, B.C. Wheeler, G.J. Brewer, and D.E.Leckband,(2000) " Long-Term Maintenace of Pattern of Hippocampal Pyramidal Cells on Substrates of Polyethlene Glycol and Microstamped Polylysine," IEEE Trans. Biomed. Eng., 47, 290-300.

Branch, D.W., Corey, J.M., Weyhenmeyer, J.A., Brewer, G.J., & Wheeler, B.C., "Micro-stamp patterns of biomolecules for high-resolution neuronal networks," Medical and Biological Engineering and Computing, vol. 36, pg. 135-141.

Corey, J.M., Brunette, A.L., Chen, M.S., Weyhenmeyer, J.A., Brewer, G.J., and Wheeler, B.C.(1997), "Differentiated B104 Neuroblastoma Cells Are a High-Resolution Assay for Micropatterned Substrates," Journal of Neuroscience Methods, 75, p 91-97, 1997.

Corey, J.M., Wheeler, B.C., and Brewer, G.J., (1996) "Micrometer resolution silane-based micropatterning of hippocampal neurons:  a comparison of photoresist and laser ablation methods for fabricating substrates," IEEE Trans. Biomed. Eng., 43, 944-955.

Wheeler, B. C., & Brewer, G. J. (1994). "Multineuron patterning and recording". In McKenna & Stenger (Eds.), Enabling Technologies for Cultured Neural Networks (pp. 167-185). Academic Press.

Corey, J.L, Wheeler, B.C., and Brewer, G.J. (1991), "Compliance of hippocampal neurons to patterned substrate networks," J. Neurosci. Res., 30, 300-307.

Conference Papers

Corey, J.M., Branch, D.W., Wheeler, B.C., Weyhenmeyer, J.A. and Brewer, G.J.  "Influencing Polarity of Hippocampal Neurons Using Micro-Stamp Patterns of Biomolecules," Abstr. 27th Soc. Neurosci. Conf., vol. 23, p. 32, New Orleans, LA, October 1997.

Branch, D.W., Corey, J.M., Wheeler, B.C., Weyhenmeyer, J.A. and Brewer, G.J. "Micro-Stamp Patterns of Biomolecules for Control of Neuronal Growth," Abstr. 27th Soc. Neurosci. Conf., vol. 23, p. 32, New Orleans, LA, October 1997.

Wheeler, B.C., Branch, D.W., Corey, J.M., Weyhenmeyer, J.A. and Brewer, G.J. "Engineering Neural Networks in Vitro: Microstamping Biomolecules to Control Cell Position," Proc. IEEE EMBS 19th Annual Int. Conf., Chicago, IL, October 1997.

Wheeler, B. C., J. M. Corey, A. L. Brunette, M. S. Chen, and J. A. Weyhenmeyer, "Micropatterning B104 Neuroblastoma Cells In Culture:  An Assay for Neuronal Pattern Synthesis", IEEE EMBS Annual Conference, Amsterdam, The Netherlands, on CD ROM, November 1996.

Corey, J. M., M. S. Chen, A. L. Brunette, D. W. Branch, J. A. Weyhenmeyer, B. C. Wheeler, and G. J. Brewer, "Influencing neuronal growth with multibiomolecule patterned substrates," 26th Soc. Neurosci. Ann. Conf., vol. 22, p. 1717, Washington, D.C.,  November 1996.

Wheeler, B.C., Corey, J.M. and Brewer, G.J., (1995), "Micropatterning of neural growth in culture:  A comparison of laser and photoresist based techniques," 188th Mtg. Electrochem. Soc., Chicago, 1995, pp. 1-8.

Corey, J.M., Wheeler, B.C. and Brewer, G.J., (1995), "Selective silane removal:  A technique for micropatterning of neurons in culture," 17th IEEE EMBS Conference, Montreal, 1995, pp. 1731-1732.

Corey, J. M., Wheeler, B. C., & Brewer, G. J. (1995). Confinement of hippocampal neurons to grid patterns using three silane-based photolithographic processes. NIH Neural Prosthesis Workshop,  Bethesda MD.

Wheeler, B.C. and Brewer, G.J., (1994), "Selective hippocampal neuritogenesis: axon growth on laminin or pleiotrophin, dendrite growth on poly-D-lysine", Soc. Neurosci. Abs., 20, p.1292, Miami Beach FL.

Wheeler, B.C. (1993), "Micropatterned neuronal cultures," Proc. 5th Iranian Biomedical Engineering Conference, Teheran.

Wheeler, B.C., Corey, J.M., and Brewer, G.J., (1993), "Patterned microcircuits of hippocampal neurons: comparisons of photoresist versus laser ablation processes," Soc. Neurosci. Abstr., 19, p. 1292, Washington DC.

Corey, J.M., Wheeler, B.C., and Brewer, G.J., (1991), "Localization of hippocampal neurons to chemically modified silicon nitride surfaces," Soc. Neurosci. Abstr., 17, p. 210, New Orleans.

Corey, J.M., Wheeler, B.C., and Brewer, G.J. (1990), "Compliancy of hippocampal neurons grown on patterned microcircuits," Soc. Neurosci. Abstr., 16, p. 1008, St. Louis.

Wheeler, B.C., Eden, G.J., and Brewer, G.J. (1989), "Patterned growth of hippocampal neurons on microcircuits," Soc. Neurosci. Abstr., 15, p. 1036, Phoenix AZ.
 

Microelectrode Arrays for Neuroscience

Journal Articles and Book Chapters

Boppart, S., Wheeler, B.C., and Wallace, C. (1992), "A flexible, perforated microelectrode array for extended neural recordings," IEEE Trans. Biomed. Eng., BME-39, 37-42.

Novak, J.L. and Wheeler, B.C. (1989), "Two-dimensional current source density analysis of propagation delays for components of epileptiform bursts in rat hippocampal slices," Brain Res., 497, 223-230.

Novak, J.L. and Wheeler, B.C., (1988) "Multisite hippocampal slice recording and stimulation using a 32 element microelectrode array," J. Neurosci. Meth., 23, 149-159.

Novak, J.L. and Wheeler, B.C. (1987), "Epileptiform activity recorded simultaneously at multiple sites on the surface of a hippocampal slice with a planar microelectrode array," 177-183, in Brain Slices: Fundamentals, Applications and Implications,- A. Schurr, T.J. Teyler, and M. Tseng (editors), S. Karger, Basel, Switzerland.

Wheeler, B.C. and Novak, J.L. (1986), "Current source density estimation using microelectrode array data from the hippocampal slice preparation," IEEE Trans. Biomed. Eng., BME-33, 1204-1212, 1986.

Novak, J.L. and Wheeler, B.C. (1986), "Recording from the Aplysia abdominal ganglion with a planar microelectrode array," IEEE Trans. Biomed. Eng., BME-33, 196-202.

Conference Papers

Wheeler, B. C., Chang, J. C., Berke, B. A., Corey, J. M. and Branch, D. W., "Technology for neuronal pattern synthesis and recording," Annals of Biomedical Engineering, p. S-68, v. 24, supplement 1,  Fall 1996 Meeting, Biomed. Eng. Soc., University Park, PA, October, 1996.

Boppart, S., Wheeler, B.C., and Wallace, C. (1991), "A flexible, porous electrode array improves longevity in hippocampal slice recordings," 14th Midwest Neuroscientists Conf., Urbana IL. (April).

Wheeler, B.C., Boppart, S., and Wallace, C. (1991), "A flexible, perforated microelectrode array for extended neural recordings," Soc. Neurosci. Abstr., 17, p. 175, New Orleans, LA.

Wheeler, B.C. and Tang, B. (1988), "A flexible electrode array for brain slice recording," Proc. 10th IEEE EMBS Conf., 816-817, New Orleans, LA.

Novak, J.L., Wheeler, B.C., and Chang, F.-L. (1987), "Variations in the delays between peaks within population bursts in CA1 recorded with a 32 element array," Soc. Neurosci. Abstr., 13, p. 942, New Orleans, LA.

Wheeler, B.C., Novak, J.L., and Smith, S.R. (1986), "32 channel microelectrode array recordings from brain slices," Proc. 19th ACEMB, 327, Baltimore, MD.

Novak, J.L. and Wheeler, B.C. (1986), "Epileptiform activity recorded from the rat hippocampal slice with a planar microelectrode array," Soc. Neurosci. Abstr., 12, p. 1528, Washington, DC.

Novak, J.L. and Wheeler, B.C. (1985), "Multi-site stimulation and recording from rat hippocampal slices using a microelectrode array," Proc. 7th IEEE EMBS Conf., 1275, Chicago, IL.

Picus, M.M. and Wheeler, B.C. (1983), "A nine channel probe for multiple neuron recording," Proc. 36th ACEMB, 224, Columbus OH.
 

Neural Signal Processing

Journal Articles and Book Chapters

Wheeler, B.C. "Real Time Techniques for Automatic Discrimination of Single Units", book chapter submitted to Methods for Simultaneous Neuronal Ensemble Recordings, M. Nicolelis (editor), CRC Press.
 
Willming, D.A. and Wheeler, B.C. (1990), "Real-time multichannel neural spike recognition with DSPs," IEEE EMBS Magazine, 9, 37-40.

Novak, J.L. and Wheeler, B.C., (1989) "A high-speed multichannel neural data acquisition system for IBM PC compatibles," J. Neurosci. Meth., 26, 239-247.

Wheeler, B.C. and Smith, S.R., (1988) "High-resolution alignment of action potential waveforms using cubic spline interpolation," J. Biomed. Eng., 10, 47-53, 1988.

Smith, S.R. and  Wheeler, B.C., (1988) "A real-time multiprocessor system for acquisition of multichannel neural data," IEEE Trans. Biomed. Eng., BME-25, 875-877.

Wheeler, B.C. & Valesano, W.R. (1985), "A real-time digital filter based data acquisition system for the detection of neural signals," Med. & Biol. Eng. & Comput., 23, 243-248.

Wheeler, B.C. and Heetderks, W.J. (1982), "A comparison of techniques for classification of multiple neural signals," IEEE Trans. Biomed. Eng., BME-29, 752-759.
Conference Papers

Wheeler, B.C., (1995) "Multineuron assemblies:  A generalized clustering  approach," International Workshop on Measures of Spatio-Temporal Dynamics, Bryn Mawr College.

Wheeler, B. C. (1994). Visualizing multineuron assemblies a generalized clustering approach. In International Symposium on the Dynamics of Neural Processing, June (pp. 79-83). Washington D.C.

Wiggins, H., Hetzel, G., Wheeler, B.C., and Lupescu, M., Hetzel, G., (1993)  "Real-time sorting of neural action potentials one hundred channels at a time," NIH Neural Prosthesis Workshop, Bethesda MD, Oct 13-15.

Zardoshti, M., Wheeler B.C., Badie, K. and Hashemi R., (1993) "Evaluation of EMG features for movement control of prostheses," Proc. IEEE EMBS 15th Annual Int. Conf., 1141-1142.

Wheeler, B.C., Fang, L., Zardoshti, M., and Wiggins, H. (1993), "Multiple unit action potential sorting: investigation of features, algorithms, and parameters for a fully automated system," Proc. IEEE EMBS 15th Annual Int. Conf., pp. 261-262.

Wheeler, B.C. and Zardoshti, M., (1993), "Advances in neural spike sorting," Proc. 5th Iranian Biomedical Engineering Conference, Teheran.

Wheeler, B.C. (1992), "Sorting action potentials one hundred channels at at a time," Proc. IEEE 14th Annual Int. Conf. IEEE EMBS, 1256-7 (invited paper).

Ozdamar, O., and Wheeler, B.C., (1992), "Real-time processing of neurological signals: neuronal and EEG spike detection using digital signal processors", invited tutorial, IEEE 14th Ann. Internat. Conf. of the IEEE EMBS  (Paris, France, Oct. 1992)

Zardoshti, M., and Wheeler, B.C. (1992), "Finding the number of neurons in extracellular recordings: a comparison of the effectiveness of popular clustering indices," Proc. Comp. Nsci. Symp., October, Indianapolis.

Fang, L., and Wheeler, B.C. (1992), "Sorting neural action potentials in extracellular recordings: a comparison of the effectiveness of popular sorting features,"  Proc. Comp. Nsci. Symp., October, Indianapolis.

Smith, S.R., Wheeler, B.C., Dowd, J.P., and Comer, C.M., (1991), "Investigation of multi-cellular neural code for directed movement," IEEE EMBS Conf., Orlando.
Wheeler, B.C. (1991), "Multi-unit neural recording," Proc. Biomed. Eng. Soc. Conf., Charlottesville VA. (October).

Dowd, J.P., Smith, S.R., Comer, C.M., and Wheeler, B.C. (1988), "Multi-unit analysis of a neural ensemble controlling directed movement," Soc. Neurosci. Abstr., 14, p. 689, Toronto.

Smith, S.R., Dowd, J.P, Wheeler, B.C., and Comer, C.M. (1988), "Analysis of multiunit data from a neural ensemble controlling directed movement," Proc. 10th IEEE EMBS Conf., 1171-1172, New Orleans, LA.

Willming, D.A. and Wheeler, B.C. (1988), "A real-time multichannel DSP-based neural signal analysis system," Proc. 10th IEEE EMBS Conf., 1169-1170, New Orleans, LA.

Wheeler, B.C. and Smith, S.R. (1988), "Neural network models of an escape response,"  Neural Networks, 1 (Suppl. 1), 281.

Wheeler, B.C. and Smith, S.R. (1987), "Action potential waveform alignment with cubic splines," Proc. 9th IEEE EMBS Conf. 1852-3, Boston, MA.

Wheeler, B.C. and Novak, J.L. (1986), "Current Source Analysis of Brain Slice Electrode Array Data", Proc. 8th IEEE EMBS Conf., 458-460, Fort Worth, TX.

Smith, S.R. & Wheeler, B.C. (1986), "A digital, real-time action potential detection system," Proc. 8th IEEE EMBS Conf., 259-262, Fort Worth, TX.

Smith, S.R. & Wheeler, B.C. (1985), "Neural signal detection techniques: performance for real-time applications", Proc. 7th IEEE EMBS Conf., 1274, Chicago, IL.

Wheeler, B.C. and Heetderks, W.J. (1980), "Performance of algorithms for the detection and classification of waveforms from individual neurons," Workshop Dig. Sign. & Waveform Anal., 5th Int. Conf. Patt. Recog., Miami Beach.

Wheeler, B.C. and Heetderks, W.J. (1980), "The effects of sampling rate on the signal-to-noise ratio of biological signals," Proc. 8th New Eng. Bioeng. Conf., 446-450, Cambridge MA.

Wheeler, B.C. and Heetderks, W.J. (1979), "Separation of cockroach giant axon action potentials using multiunit analysis techniques," Proc. 7th New Eng. Bioeng. Conf., 310-313, Troy NY.
 

Other Papers

Journal Articles and Book Chapters

Gordon, S. H., Schudy, R. B., Wheeler, B. C., Wicklow, D. T., & Greene, R. V., (1997) "Identification of Fourier transform infrared photoacoustic spectral features for detection of aspergillis flavus infection in corn," Int. J. Food Microbiol., 35, 179-185.

Zardoshti-Kermani, M., Wheeler, B. C., Badie, K., & Hashemi, R. M. (1995). EMG feature evaluation for movement control of upper extremity prostheses. IEEE Trans. Rehab. Eng., 3(4), 324-333.

Gordon, S.H., Greene, R.V., Wheeler, B.C., and James, C., (1993), Multivariate FTIR analysis of substrates for protein, polysaccharide, lipid and microbe content: Potential for solid-state fermentations,  Advances in Biotechnology, vol. 11, pp. 665-675.

Conference Papers

Liu, C., Feng, A.S., Wheeler, B.C., O'Brien, W.D., Bilger, R.C. and Lansing, C.R. "A binaurally-based auditory processor effectively extracts speech in the presence of multiple competing sounds," Hearing Aid Research and Development Conference, NIH, Bethesda, MD, September 1997.

Bendre, A., Swain, R., Wheeler, B.C., & Greenough, W. (1995). Augmentation of cerebellar responses to parallel fiber activation following skilled motor acquistion in rats. ", Soc. Neurosci. Abstr., 21, San Diego, CA.

Stavrakos, N. J., Wheeler, B. C., Gordon, S. H., Wicklow, D. T., Greene, R. V., & Schudy, R. B. (1994). Identification of contaminated corn from FTIR spectra:  A MATLAB tool for pattern recognition and neural network studies. In C. H. Dagli,F. R. Fernandez,J. Ghosh, & R. T. S. Kumara (Ed.), Artificial Neural Networks in Engineering, 4 (pp. 779-784). St. Louis, MO.

Peck, T.L., LaValle, L., Magin, R.L., Adesida, I., and Wheeler, B.C. (1993), "RF Microcoils with Micron-Scale Feature Sizes for NMR Microscopy," Proc. IEEE EMBS 15th Annual Int. Conf., pp. 174-175.

Wheeler, B.C., Gordon, S.H., DeWispeleare, D.R., Jackson, M.A., and Greene, R.V. (1993) "Neural Network Identification of Contaminated Corn from FTIR Spectra," Proc. IEEE EMBS 15th Annual Int. Conf., pp. 301-302.

Wheeler, B.C., (1993), "Matlab exercises to demonstrate principles of biological modeling and signal processing," Proc. 100th Annual Conference ASEE, 1789-1790, Champaign IL.

Brusnighan, D.A., Strauss, M.G., Floyd, J.M., and Wheeler, B.C., (1989) "Orientation aid implementing the global positioning system," Proc. NE Bioeng. Conf., Boston.
Kim, M., Shin, K.G., and Wheeler, B.C. (1978), "A systems model of cell kinetics and its application to cancer chemotherapy," Proc. Joint Automatic Control Conf.